Vaccine Requirements & Info | South Carolina Department of Public Health

Pink banner with various children. Text under: Get ready for the new school year! Put vaccines on your child's back to school list.

Make Sure Your Child is Up to Date with All Recommended Vaccines

Don't wait until the end of the summer! Schedule an appointment early with your child's health care provider or health department to get vaccinated. Vaccines are important to protect our kids from diseases such as measles, mumps, chickenpox and whooping cough.

2025-2026 School Year: Click here for 2025-2026 school year vaccination requirements

COVID-19 vaccines are not required. As of September 2024, the updated 2024-2025 COVID-19 vaccines are available and authorized for everyone 6 months of age and older. As always, DPH encourages people to speak with their health care provider to evaluate the risks and benefits of vaccination. See COVID-19 prevention and vaccination to learn more.

South Carolina Vaccine Requirement Information for Parents

Childcare

Childcare Immunization Info for Parents

Green header with white text of linked file: VACUNACIÓN EN LOS CENTROS DE CUIDADO INFANTIL INFORMACIÓN PARA PADRES

Infancia de Inmunizacion Infantil para Padres

K-12

5K - 12 Immunization Info for Parents

Blue header with white text of linked file- VACUNACIÓN DE 5K A 12.° GRADO INFORMACIÓN PARA PADRES

5K - 12 Información de Inmunización Para los Padres

Resources for Health Care Providers, Childcare Providers & School

Immunization Requirements for Childcare & Schools, 2025-2026 (pdf)

Childcare & School Vaccine Requirements Archive

Refugee Immunization Information

This section only applies to children who are refugees.
Children considered refugees should receive the required vaccines if immunization documentation is not available.
Hepatitis B Vaccination exception:
- In general, Hepatitis B serology should not replace completion of the routine Hepatitis B series.
- If a provider chooses to draw Hepatitis B titers:
  - The serologic markers most widely used in the diagnosis of acute, chronic, resolved HBV infection, and/ or vaccine immunity include HBV surface antigen (HBsAg), antibody to HBsAg (anti-HBs), and antibody to HBcAg (total and IgM anti-HBc). See Expanded Hepatitis B Serologic Marker Interpretation and Initial Management Table (CDC)
  - Resource: CDC Hepatitis B resource regarding hepatitis serologies and interpretation of results for refugees.
- If the titers indicate Hepatitis B immunity, the provider must document all of the following information on the South Carolina Certificate of Immunization (D-4024) line corresponding to Hepatitis B:
  - "Positive Titer - Hep B"
  - Date of titer