Updated Oct. 10, 2025
Prevention
Things you can do to reduce your chance of getting or spreading COVID:
- Wash your hands regularly
- Cover your cough
- Stay home if you are sick
- Stay up to date on your vaccinations
If you begin experiencing any symptoms, monitor them, and talk with your health care provider about possible treatments. See our COVID-19 Symptoms and Treatment page for more information.
Vaccine Information
The updated 2025-2026 COVID-19 vaccines are available and authorized for people on the CDC High Risk for COVID list. DPH continues to recommend that people speak with their health care provider to evaluate individual risks and benefits of vaccination.
Because COVID-19 is still causing illness, hospitalizations and even deaths, DPH especially recommends those at greatest risk for severe COVID-19 receive the COVID-19 vaccine. This includes people who are:
- 65 years and older
- Have a medical condition that puts you at high risk for severe COVID
- Live in a long-term care facility
- Pregnant or breastfeeding
Currently Available COVID Vaccines AND AUTHORIZED USES
| Vaccine | Authorized for: |
|---|---|
| Moderna Low-Dose Vaccine (mNexspike) | Adults 65 and older, and people age 12 to 64 who have a least one health condition that puts them at increased risk from the coronavirus. |
| Moderna COVID-19 Vaccine (Spikevax) | Adults 65 and older, and people age 6 months to 64 years who have a least one health condition that puts them at increased risk from the coronavirus. |
| Pfizer-BioNTech COVID-19 Vaccine (Comirnaty) | Adults 65 years of age and older, and people age 5 to 64 who have a least one health condition that puts them at increased risk from the coronavirus. |
| Novavax COVID-19 Vaccine | Adults 65 years of age and older, and people age 12 to 64 who have a least one health condition that puts them at increased risk from the coronavirus. |
Where Can I Get a COVID-19 Vaccine?
Many doctors’ offices, community health clinics or pharmacies will offer the current COVID-19 vaccine. Call a provider or pharmacy to see if they have the current COVID-19 vaccines available.
DPH Health Departments/Clinics
DPH anticipates having the current Moderna Spikevax COVID-19 vaccine for children who are eligible for the Vaccines for Children Program (ages 6 months to 18 years) and adults who are uninsured or have limited insurance in mid-October 2025. South Carolinians can visit the Public Health Clinics page or call 1-855-472-3432 for an appointment after the week of Oct. 13, 2025.
DPH will offer vaccines to the age groups indicated in the FDA's authorizations for people on the CDC High Risk for COVID list.