Updated: Aug. 10, 2026
Renewal Application
DPH does not have an online renewal process. Renewal applications must be sent through U.S. postal mail to the address on the application.
If you are attempting to renew an "active" (not expired) S.C. Controlled Substances Registration or if you have not received a renewal application, use the renewal application:
If you have not received your certificate of registration, you may print a duplicate:
If you are not renewing, please email bdcrenewals@dph.sc.gov to request cancellation to avoid a $100 penalty fee if you need to re-register in the future.
Deadlines
| Provider Type | When DPH Sends Renewal Applications | When Registrations Must be Renewed |
|---|---|---|
| MDs, DOs and EMS Units | Third week of July | October 1 |
| DMD, DDS, DVM, OD, APRN, PA-C, pharmacies and all other registrants | Third week of January | April 1 |
To allow DPH adequate time for processing renewal applications, we recommend that you submit the renewal application at least 10 days before the registration expiration date.
What if My Registration Expires?
The registration of a registrant who fails to renew by April 1 or October 1, whichever is applicable, is expired. On May 18, 2018, the South Carolina Controlled Substances Act eliminated the registration grace period. See the South Carolina Code of Laws Section 44-53-280 (C & D) for details.
To reinstate an expired registration, a new application must be submitted with a payment of the registration fee plus a $100 penalty fee. All applications must be submitted through U.S. postal mail to the Bureau of Drug Control. Processing time is approximately 12-15 business days. Visit DPH's New Registrations webpage for more information.
Providers are not authorized to prescribe, administer, possess or dispense controlled substances until their S.C. Controlled Substances Registration is reinstated.
Check on the Status of a Renewed Controlled Substance Registration
Renewal processing takes up to 10 business days.
Check on the status of your renewal:
If you cannot find your registration or you have already paid your fees but your registration still shows as expired, and it has been at least 10 business days since you submitted your renewal to the department, contact the Bureau of Drug Control at bdcrenewals@dph.sc.gov or 803-896-0636 for assistance.
Registration Fee Receipt
If you cannot find your receipt, please check your email’s spam and junk folders. Receipts are automatically sent to the email address used at the time of payment.
If you still cannot locate the receipt for an SC Controlled Substances registration fee, please email Accounts Receivables at Receivables@dph.sc.gov.