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COVID-19 Vaccines

Two types of COVID-19 vaccines are recommended for use in the United States:

1. mRNA vaccines
   • Age 6 months to 11 years
     • Moderna COVID-19 Vaccine-2024–2025 Formula
     • Pfizer-BioNTech COVID-19 Vaccine-2024–2025 Formula
   • 12 years and older
     • SPIKEVAX is the licensed Moderna product for people ages 12 years and older.
     • COMIRNATY is the licensed Pfizer-BioNTech product for people ages 12 years and older.
2. Protein subunit vaccine
   • Novavax COVID-19 Vaccine, Adjuvanted (2024–2025 Formula) is authorized for people ages 12 years and older.

These are the only COVID vaccines that should be used as of March 2025.

There is no preferential recommendation for the use of any one COVID-19 vaccine over another when more than one recommended and age-appropriate vaccine is available.

Monoclonal Antibodies

Pemgarda (pemivibart) is a human monoclonal antibody that has received emergency use authorization (EUA) for the prevention of coronavirus disease 2019 (COVID-19) in high-risk immunocompromised adults and adolescents 12 years of age and older who weigh at least 40kg. Candidates:

• Cannot be currently infected with SARS-CoV-2 or have had a known recent exposure to an individual infected with SARS-CoV-2
  And
• Must be moderately to severely immune compromised due to a medical condition (such as blood cancer) or receipt of immunosuppressive medications or treatments (such as an organ transplant) and be unlikely to mount an adequate immune response to COVID-19 vaccination.

Pemgarda was issued an EUA on March 22, 2023. It is not FDA-approved for any use.