Renewal Application

DPH does not have an online renewal process. Renewal applications must be sent through U.S. postal mail to the address on the application.

If you are attempting to renew an "active" (not expired) S.C. Controlled Substances Registration, use the renewal application:

If you have not received a renewal application, you may print a duplicate:

• SC Controlled Substances Act
• SC Controlled Substances Regulation (60-4) (pdf)
• SC Prescription Monitoring Act (pdf)
• Buprenorphine
• US Drug Enforcement Administration
• SC Pharmacy Practice Act

To make changes to your practice location address, registrant name, or drug schedules on your current DPH controlled substances registration, follow the applicable instructions below. To make corresponding changes to your current DEA registration, follow the applicable instructions on the DEA’s website.

To cancel a registration, a letter can be emailed to bdc@dph.sc.gov or faxed to 1-803-896-0627, Attention: Renewal Clerk, referencing your South Carolina Controlled Substance Registration number and Federal DEA number, stating that you are requesting to cancel your registration due to whatever the reason may be, e.g., moving out-of-state, retired, no longer practicing your profession, or you no longer possess a valid South Carolina practitioner license.

Updated: Apr. 17, 2026

Annual Inventory Requirement

Inventories shall be taken on May 1 of each year unless written permission for another date is granted by the Bureau of Drug Control. If permission for another date is granted, the registrant shall maintain documentation of such permission for a period of two (2) years. In the event that a person commences business with no controlled substances on hand, he or she shall record this fact as his or her initial inventory.

• Disbursement Request for Contribution Distribution (.xlsx)
• Contribution Expenditure Report (.xlsx)

For additional information, please contact Andrew Whitmire: whitmiar@dph.sc.gov, (803) 898-7210.

Updated: April 30, 2026

The Certificate of Need Program administers a regulatory regime known as the State Certification of Need and Health Facility Licensure Act (hereinafter referred to as the "Act") that is set forth in S.C. Code Sections 44-7-110 to 44-7-230. 

The purpose of the Act is to promote cost containment, prevent unnecessary duplication of health care facilities and services, guide the establishment of health facilities and services which will best serve public need and ensure high quality services are provided in health facilities in this State.

EMT-Basic candidates who successfully complete a South Carolina-approved EMT-Basic course that uses the 1994 DOT EMT-Basic curriculum; successfully pass the National Registry EMT-Basic (i.e. the State of S.C. basic written and practical examinations); and receive subsequent South Carolina certification as an EMT-Basic, are authorized to perform the following skilled activities (all skills can be used on adult, child and infant patients unless otherwise stated):

Updated: Dec. 10, 2025